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Objective This study is to find valid medication to improve the condition of bone marrow suppress in a short period of time after chemotherapy of female genitalia cancer and to create a condition for second - time chemotherapy. Method Thirty- five cases using rhG- CSF were included in the experiment group while cases without rhG - CSF were set as control group. The wbc level in two groups are compared. Result The comparison shows that wbc resumes normal within 22 days in the experiment group while 35 days in the control group. The duration is 13 days less in the experiment group than the control group. From the 21st day after chemotherapy, patients in the experiment group need 2.5 days before another chemotherapy while 12 days for the control group. The average account of wbc in the experiment group is 9.5 × 109/L while 6.2 × 109/L in the control group. The variation in the comparison of 3 groups of data is statistically significant (P < 0.05). Conclusion The above results show that rhG - CSF has positive efficacy on the treatment of bone marrow suppress after chemotherapy of female genitalia cancer and helps the regular chemotherapy proceed smoothly.