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美国临床实验室标准化研究所(CLSI,先前的NCCLS)修正了金葡菌对万古霉素的敏感性和抗性临界值,即万古霉素敏感菌的MIC由原来的4μg/mL改为2μg/mL,万古霉素中介菌的MIC由先前的8~16μg/mL改为4~8μg/mL。更改该万古霉素MIC执行标准的主要依据是:(1)来自美国和欧洲的体外敏感性数据;
The American Society for Clinical Laboratory Standards (CLSI, formerly NCCLS) amends the threshold of susceptibility and resistance to S. vancomycin to S. vancomycin by changing the MIC of vancomycin-susceptible bacteria from 4 μg / mL to 2 μg / mL, and the MIC of vancomycin-producing bacteria was changed from 8 ~ 16μg / mL to 4 ~ 8μg / mL. The main basis for altering the implementation of this vancomycin MIC is: (1) in vitro sensitivity data from the United States and Europe;