先天性尿道下裂是泌尿生殖系统常见的先天性畸形之一,其发病率有逐年上升的趋势[1]。近年来对先天性尿道下裂的发病原因作了大量深入的研究,特别是对严重的尿道下裂的研究表明:先天性尿道下裂不只是局部的发育畸形,而且是全身内分泌缺陷的一个局部表现[2],常常伴有阴茎发育不良 Congenital hypospadias genitourinary system is one of the common congenital malformations, the incidence has increased year by year trend [1]. In recent years, the incidence of congenital hypospadias made a lot of in-depth study, especially for severe hypospadias research shows that: congenital hypospadias is not just the local developmental deformity, but also a part of the systemic endocrine defects Performance [2], often accompanied by penile dysplasia