下颔—眼—面—头颅发育异常综合征是一不太常见的综合征。1948年首次由Hall-ermann 描述了鸟脸畸型合并先天性白内障的病人;1950年S′treiff 又报道了下颌及颜面异常合并先天性白内障,故定名为下颌一眼—面—头颅发育异常综合征,又称Hall-ermann-Streiff 综合征。1958年Francoi 总结本综合征的主要临床特点为头颅发育异常和特征性鸟脸,牙齿异常,侏儒,毛发稀少,皮肤萎缩,双侧小眼球和先天性白内障。在所有病人中,均有头颅发育异常和鸟脸畸型。眼部病变除白内障外,青光眼是最 Hyponatra - eye - face - Cranial dysplasia syndrome is a less common syndrome. In 1948, for the first time, Hall-ermann described the patients with bird face deformity complicated with congenital cataracts. In 1950, S’treiff reported the congenital cataract with mandibular and facial abnormalities, so named as mandibular craniovelli- Also known as Hall-ermann-Streiff syndrome. 1958 Francoi Summary The main clinical features of this syndrome are cranial dysplasia and characteristic bird faces, abnormal teeth, dwarfism, rare hair, skin atrophy, bilateral small eyeballs and congenital cataracts. In all patients, there are skull dysplasia and bird face deformity. Eye disease In addition to cataracts, glaucoma is the most