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目的 :研究急进高原健康人的血液流变学变化。方法 :采用北京普利生集团公司生产的LBY -N6型旋转式血液流变自动分析仪。测定急进格尔木组 (海拔 2 80 0m ,n =2 8) ,沱沱河组 (海拔 4 70 0m ,n =2 8) ,健康志愿者血液流变学项目。结果 :格尔木组的全血粘度、血浆粘度、全血还原粘度、红细胞压积分别为 (13.6 6± 3.6 1)mPa s、(1.81± 0 .2 2 )mPa s、(2 4 .86± 4 .6 7)mPa s、(5 0 .31±5 .4 9) % ;沱沱河组分别为 (2 0 .5 6± 4 .10 )mPa s、(2 .0 4± 0 .2 9)mPa s、(2 9.5 6± 3.91)mPa s、(6 4.79± 5 .32 ) % ,差别有显著性 (P <0 .0 0 1)。在低切变率及高切变率下全血粘度 ,全血还原粘度均升高明显 ,间接提示红细胞的聚集性增强 ,变形性减弱。结论 :随着海拔的升高 ,血液流变学检测指标有明显的变化 ,具有“浓、粘、聚、凝”的特点
Objective: To study the changes of hemorheology in healthy people in rapid plateau. Methods: The LBY-N6 rotary blood rheology analyzer produced by Beijing Pulisheng Pharmaceutical Group was used. The acute Golmud group (elevation 2 80 0 m, n = 2 8) and the Tuotuohe group (elevation 4 70 0 m, n = 28) were measured in the hemorheology project of healthy volunteers. Results: The whole blood viscosity, plasma viscosity, whole blood reducing viscosity and hematocrit in Golmud group were (13.66 ± 3.6 1) mPa s, (1.81 ± 0.22) mPa s, (24.8 ± 4) .6 7) mPa s, (5 0 .31 ± 5. 49)%, respectively; Tuotuohe Formation was (20.56 ± 4.10) mPa s, (2.04 ± 0.29 ) mPa s, (2 9.56 ± 3.91) mPa s, (4.79 ± 5.32)%, respectively, with a significant difference (P <0.001). In the low shear rate and high shear rate of whole blood viscosity, reduced viscosity of whole blood were significantly increased, suggesting that red blood cell aggregation increased indirectly, reduced deformability. CONCLUSION: With the elevation of altitude, there are significant changes in the indexes of hemorheology, with the characteristics of “thick, sticky, aggregated and condensed”