70年代末以来,多胎妊娠明显增加,其原因主要是妇科内分泌和生殖医学领域的迅速发展。在德国,助孕术后多胎妊娠为25%,80%以上3胎和3胎以上的多胎是因激素刺激治疗或助孕所致。 目前尚无明确的数据表明,不孕症治疗方式与多胎妊娠率的明确关系。尽管助孕术导致多胎妊娠增多,但大多是卵巢刺激治疗使体内受孕。常用刺激卵巢药物对多胎妊娠的影响:克罗米芬治疗后多胎妊娠为5%～10%,其中95%为双胎,3胎和4胎各占3.5%和1.5%。促性腺激素(HMG、FSH)治疗 Since the late 1970s, there has been a marked increase in multiple pregnancy, mainly due to the rapid development of gynecological endocrinology and reproductive medicine. In Germany, more than 25% of pregnancies with multiple pregnancies result in more than 80% of 3 and more than 3 births due to hormone therapy or pregnancy. There is no clear data that shows a clear relationship between infertility treatment and multiple pregnancy rates. Although pregnancy-assisted surgery leads to an increase in multiple pregnancies, most of them are ovarian stimulation treatments that confer in-body conception. Common stimulation of ovarian drugs on multiple pregnancy: Clomiphene after treatment of multiple pregnancies of 5% to 10%, of which 95% were twins, 3 and 3 tires accounted for 3.5% and 1.5%. Gonadotropin (HMG, FSH) treatment