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[目的]探讨小儿慢性胃炎中医证型与胃黏膜改变及幽门螺杆菌感染之间的内在关系。[方法]将符合入选条件的404例慢性胃炎患儿中医辨证分型后进行胃镜检查及尿素13 C-呼气试验(13 C-UBT)检查,并登记造表,进行统计学处理。[结果]肝胃不和型胃炎主要表现为胃黏膜充血和微小结节形成,脾胃湿热型胃炎表现以黏膜斑和黏膜糜烂为主,胃络瘀血型胃炎则以胃黏膜出现出血斑点为主,脾胃虚弱型胃炎以胃黏膜水肿为主,胃阴不足型胃炎以胃黏膜花斑为主。13 C-UBT阳性率实证高于虚证,与证型无相关性;13 C-UBT值实证高于虚证,尤以肝胃不和型和脾胃湿热型为最高。[结论]小儿慢性胃炎中医辨证分型与胃黏膜改变及幽门螺杆菌感染之间存在实质性联系,为辨证施治提供了理论基础。
[Objective] To explore the relationship between TCM syndromes of chronic gastritis and gastric mucosal changes and Helicobacter pylori infection in children. [Method] 404 cases of children with chronic gastritis were enrolled in this study. Gastroscopy and 13 C-UBT (urea-13 C-UBT) were used to diagnose and differentiate children with chronic gastritis. [Results] The main manifestations of gastroparesis of stomach and stomach were gastric mucosal congestion and tiny nodule formation. The spleen-stomach damp-heat type of gastritis manifested mainly mucosal plaque and mucosal erosion. Gastric stasis-type gastritis mainly manifested bleeding spots in gastric mucosa. Stomach weakness gastritis mainly gastric mucosal edema, gastric insufficiency gastritis gastric mucosa based. The positive rate of 13 C-UBT was higher than that of deficiency syndrome, and had no correlation with syndrome type. The 13 C-UBT value was higher than that of deficiency syndrome, especially the liver-stomach disagreement and spleen-stomach damp-heat syndrome were the highest. [Conclusion] There is a significant correlation between TCM syndrome differentiation of chronic gastritis and gastric mucosal changes and Helicobacter pylori infection, providing a theoretical basis for syndrome differentiation and treatment.