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为了考察微重力在分子水平上的效应，特别是对水溶剂结构的影响，测定了空间和地面生长的多个鸡蛋清溶菌酶晶体和蝮蛇毒酸性磷脂酶Ａ２晶体的结构，并做了结构比较研究。结果表明，虽然微重力不足以改变蛋白质肽链的构象及与蛋白质分子联系较强的溶剂分子的结合状况，但微重力可能改善与蛋白质分子联系较弱的有序水分子结构。这两种蛋白质晶体的结构测定结果也提示，微重力下蛋白质晶体质量改善的显示程度可能与蛋白质晶体的溶剂含量相关。这些发现从一个方面揭示了微重力改进蛋白质晶体质量的机理。另外，考虑到水分子对生命活动的重要性，这一初步结论的确认可能会对深入开展微重力生命科学研究有所启示。
In order to investigate the effect of microgravity at the molecular level, especially on the structure of water solvents, the structures of several egg white lysozyme crystals and viper venom acidic phospholipase A2 crystals grown in space and on the ground were determined and compared in structure the study. The results showed that although microgravity was not enough to change the conformation of protein peptide chains and the binding of solvent molecules with strong contact with protein molecules, microgravity might improve the orderly water molecule structure which is weakly linked with protein molecules. The results of the structure determination of the two protein crystals also suggest that the degree of improvement in the quality of protein crystals under microgravity may be related to the solvent content of the protein crystals. These findings reveal in one aspect the mechanism by which microgravity improves the quality of protein crystals. In addition, considering the importance of water molecules to life activities, the confirmation of this preliminary conclusion may give some insights into the further development of microgravity life science research.