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目的通过对妊娠早期症状与经前期症状之间的相关性分析,评估经前期症状对妊娠早期症状的预测价值。方法对2014年9~12月在郑州大学第一附属医院产科就诊的305例妊娠期妇女进行问卷调查,采用配对t检验对经前期症状和妊娠早期症状进行差异性分析,分别采用简单线性回归模型、多重线性回归模型对经前期症状与妊娠早期症状进行相关性分析。结果妊娠早期症状出现的频数及严重程度与经前期症状比较,差异均有统计学意义(t=6.9、t=6.7,P<0.001);妊娠早期与经前期各症状平均严重程度之间存在大量的相关性;妊娠早期症状的总体严重程度与经前期症状的总体严重程度呈显著性相关(b=0.4,95%CI=0.3~0.5,P<0.001)。结论妊娠早期与经前期具有相似的症状模式,妊娠早期出现的某一精神心理症状可通过经前期症状预测,经前期易怒症状的严重程度是预测妊娠早期症状总体严重程度的最佳指标。
Objective To evaluate the predictive value of premenstrual symptoms on early pregnancy symptoms by analyzing the correlation between early pregnancy symptoms and premenstrual symptoms. Methods A total of 305 pregnant women in obstetrics department of the First Affiliated Hospital of Zhengzhou University from September to December 2014 were investigated by questionnaire. Paired t-test was used to analyze the differences of premenstrual symptoms and early pregnancy symptoms. The simple linear regression model , Multiple linear regression model of premenstrual symptoms and early pregnancy symptoms were analyzed. Results The frequency and severity of symptoms in early pregnancy were significantly different from those in premenstrual symptoms (t = 6.9, t = 6.7, P <0.001). There was a large number of average severity of symptoms between early pregnancy and premenstrual The overall severity of early pregnancy symptoms was significantly associated with the overall severity of premenstrual symptoms (b = 0.4, 95% CI = 0.3-0.5, P <0.001). Conclusions Early pregnancy has the similar symptom pattern with premenstrual syndrome. One of the mental and psychiatric symptoms in early pregnancy may be predicted by premenstrual symptoms. The severity of premenstrual symptoms of irritability is the best predictor of the overall severity of early pregnancy symptoms.