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目的:评价高频超声引导下乳腺钙化微创切除活检术的临床应用价值。方法:选取我院2012年9月至2014年9月收治的66例乳腺钙化患者,患者均行高频超声引导下的微创切除活检;分析乳腺钙化取出的活检成功率、病理结果及钙化灶微创活检的临床影响因素。结果:乳腺钙化灶的活检成功率为72.9%(51/70),弥散性钙化46侧、成功率为65.2%(30/46),钙化伴肿块24侧、成功率为87.5%(21/24);钙化范围≤5 mm钙化取出活检成功率为55.9%,而钙化范围>5 mm为88.9%;经X2检验单因素分析,钙化取出活检成功率与钙化类型和钙化范围有关(P<0.05);Logistic多因数回归分析发现钙化灶的类型和范围是影响钙化灶微创活检的主要因素(P<0.05)。结论:高频超声引导下乳腺钙化微创切除活检成功率与钙化类型和钙化范围有关,其中钙化范围>5 mm成功率最高,有较好的临床价值。
Objective: To evaluate the value of ultrasonography-guided breast minimally invasive biopsy in breast cancer. Methods: Sixty-six patients with breast calcification were selected from September 2012 to September 2014 in our hospital. Patients underwent minimally invasive biopsy guided by high-frequency ultrasound. The biopsy success rate, pathological findings and calcification of breast calcification Clinical influencing factors of minimally invasive biopsy. Results: The success rate of biopsy of breast calcification was 72.9% (51/70), diffuse calcification was 46, the success rate was 65.2% (30/46), and the calcification was associated with 24 sides of the tumor with a success rate of 87.5% (21/24 ). The success rate of calcification within 5 mm was 55.9% for calcification and 88.9% for calcifications> 5 mm. The univariate analysis showed that the success rate of calcification with biopsy was related to calcification type and calcification range (P <0.05) Logistic regression analysis showed that the type and extent of calcification were the main factors influencing minimally invasive biopsy of calcification (P <0.05). CONCLUSION: The success rate of minimally invasive breast biopsy under the guidance of high-frequency ultrasound is related to the type of calcification and the range of calcification. The calcification range> 5 mm has the highest success rate and good clinical value.