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目的多虑平和三联双歧杆菌合用治疗肠易激综合征(IBS)及其伴随的焦虑和抑郁症状的临床治疗效果。方法选择104例患者,随机分为三联双歧杆菌合用多虑平治疗组与谷维素对照组,治疗4周.通过对临床消化道症状的改善评定治疗效果,同时采用汉密顿焦虑量表(HAMA)和抑郁量表(HAMD)进行评分观察治疗前后抑郁和焦虑的改善程度。结果两组治疗后IBS病人消化道症状、精神心理量表评定总分均较治疗前改善,且治疗组明显优于对照组。结论多虑平合用三联双歧杆菌对改善IBS患者的肠道症状和肠外焦虑与抑郁症状有显著疗效,可作为治疗IBS的较好方法。
Objective To treat patients with irritable bowel syndrome (IBS) and anxiety and depressive symptoms associated with Doudoune and Bifidobacterium triple therapy. Methods 104 patients were randomly divided into three levels of Bifidobacterium combined with doxepin treatment group and oryzanol control group for 4 weeks.The therapeutic effect was evaluated by improving the clinical gastrointestinal symptoms.At the same time, the Hamilton Anxiety Scale (HAMA) ) And Depression Scale (HAMD) were scored to observe the improvement of depression and anxiety before and after treatment. Results After treatment, the scores of gastrointestinal symptoms and mental health assessment in IBS patients were better than those before treatment, and the treatment group was significantly better than the control group. Conclusions Duoxepine and Bifidobacterium triple Bifidobacterium have a significant effect on improving intestinal symptoms and parenteral anxiety and depressive symptoms in patients with IBS, which may be a good method for the treatment of IBS.