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目的分析与探讨COPD与哮喘患者的气道高反应性。方法选取本院2011年11月至2012年11月期间收治的哮喘患者共40例,COPD患者共40例,所有患者在接受随访的过程中均处于稳定期。对两组患者进行支气管组胺激发试验,以了解患者的FEF25%-75%/FVC的变化。结果 COPD患者的各项指标明显低于哮喘患者,P<0.05,气道容积越小,则气道的收缩能力越强,反应性也相对越高。结论 COPD与哮喘患者的气道高反应性具有显著性差异,哮喘患者发生高气道反应的几率明显高于COPD患者。
Objective To analyze and explore the airway hyperresponsiveness in patients with COPD and asthma. Methods Forty patients with asthma admitted to our hospital from November 2011 to November 2012 were enrolled. A total of 40 patients with COPD were included in the study. All patients underwent stable follow-up. Bronchial histamine challenge was performed on both groups to understand the changes in patients with FEF25% -75% / FVC. Results The indexes of COPD patients were significantly lower than those of asthmatic patients (P <0.05). The smaller the airway volume, the stronger the airway contractility and the higher the reactivity. Conclusions The airway hyperresponsiveness in patients with COPD and asthma is significantly different. The incidence of high airway response in patients with asthma is significantly higher than that in patients with COPD.