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感染存在时不能达到充分的局麻是众所周知的临床问题,但对其机理却所知甚少。材料与方法: 作者用30只体重2公斤的雄性新西兰白兔作动物实验,共分为三组,每组10只。所有动物均以50毫克硫苯妥钠麻醉。在无菌条件下,于右下颌切牙区施行手术,造成一标准的根尖周缺损;并作手术暴露右侧股神经。第一组,在远离手术伤口,接近右下颌神经和股神经处注射0.2% Carbocaine。第二组,用0.1%甲醛甲酚注入右侧根尖周缺损和右侧股神经。其中5只动物如第
It is a well known clinical problem that sufficient local anesthetic can not be achieved in the presence of infection, but little is known about its mechanism. MATERIALS AND METHODS: Thirty male New Zealand white rabbits weighing 2 kg were used as experimental animals and divided into three groups of 10 rats each. All animals were anesthetized with 50 mg of thiopental. Under aseptic conditions, surgery was performed in the right mandibular incisor area, resulting in a standard periapical defect; surgery was performed to expose the right femoral nerve. In the first group, 0.2% Carbocaine was injected near the right mandibular and femoral nerves away from the surgical wound. In the second group, right apical defect and right femoral nerve were infused with 0.1% formaldehyde cresol. Five of them were the same