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目的：用１８８Re标记单抗C５９５，鉴定标记物特性，实验膀胱内给药治疗膀胱癌的效果。方法：单抗C５９５（抗MUC１粘蛋白，IgG３），从经MUC１尿粘蛋白免疫的BALB／c鼠取脾细胞，按常规杂交瘤技术制备；非特异对照单抗为１H１１（抗尘螨抗原，用９９Tcm标记）。核素１８８Re
OBJECTIVE: To characterize the characteristics of markers using 188Re labeled monoclonal antibody C595 and evaluate the effect of intravesical administration on bladder cancer. Methods: Monoclonal antibody C595 (anti-MUC1 mucin, IgG3) was prepared from BALB / c mice immunized with MUC1 urinary mucin by conventional hybridoma technique. The nonspecific control mAb was 1H11 (anti-dust mite antigen, Labeled with 99 Tcm). Nuclide 188Re