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[目的]探讨重型颅脑损伤患者早期肠内营养方式的可行性和临床效果。[方法]120例重型颅脑损伤患者按病人的住院号分为A、B两个观察组,每组各60例,A组应用容量泵间歇性输注肠内营养,B组用容量泵24h持续均匀输注肠内营养。对照两组营养状况指标(血红蛋白、总蛋白、血清白蛋白、氮平衡、血淋巴细胞值、TSF、AMC、血糖等)以及呕吐返流、腹泻腹胀、胃肠道出血、肝功损害及电解质紊乱等并发症发生率。[结果]营养指标观察显示两组营养效果接近,两组临床检查数据比较氮平衡、血红蛋白、白蛋白、电解质、淋巴细胞总数、TSF、AMC值,差异无统计学意义(P﹥0.05)。但血糖血糖控制、并发症比较,差异有统计学意义(P﹤0.05);两组呕吐返流发生率、肝功能异常对比,差异无统计学意义(P﹥0.05);A组胃潴留、腹泻、反复消化道出血、二重感染的发生率低于B组,差异有统计学意义(P﹤0.05)。[结论]间歇输注与连续输注营养效果接近,间歇输注比连续输注有更多活动时间,类似于正常膳食的间隔,其胃潴留、腹泻、反复消化道出血、二重感染等并发症的发生率较低。
[Objective] To investigate the feasibility and clinical effect of early enteral nutrition in patients with severe craniocerebral injury. [Methods] 120 patients with severe craniocerebral injury were divided into A and B groups according to patient’s hospitalization number, 60 cases in each group. Group A received intermittent infusion of parenteral nutrition with volume pump, and group B received 24h Continuous infusion of enteral nutrition. The indexes of nutritional status (hemoglobin, total protein, serum albumin, nitrogen balance, blood lymphocyte count, TSF, AMC, blood glucose, etc.) were compared between the two groups in terms of vomiting reflux, diarrhea, gastrointestinal bleeding, liver damage and electrolyte imbalance Other complications. [Results] The results of nutritional indicators showed that the nutritional effects of the two groups were similar. The nitrogen balance, hemoglobin, albumin, electrolytes, total lymphocytes, TSF and AMC were not significantly different between the two groups (P> 0.05). (P <0.05). There was no significant difference between the two groups in the incidence of vomiting reflux and abnormal liver function (P> 0.05). A group of gastric retention and diarrhea , Recurrent gastrointestinal bleeding, the incidence of double infection was lower than that of group B, the difference was statistically significant (P <0.05). [Conclusion] Intermittent infusion and continuous infusion have similar nutritional effects. Intermittent infusion has more activity time than continuous infusion, which is similar to the interval of normal diet, with gastric retention, diarrhea, recurrent gastrointestinal bleeding and double infection The incidence of disease is low.