论文部分内容阅读
在体外培养骨髓瘤单核细胞系(M20)的上清液具有抑制白细胞介素1(IL1)的活性。从其上清液中分离出一种因子,该因子能抑制由IL1诱导的小鼠胸腺细胞对PHA反应的增殖,也能抑制依赖IL1的淋巴细胞和成纤维细胞的增殖,但不能抑制IL2诱导的或与IL1无关的其它细胞增殖反应。从正常人外周血单个核细胞(PBMC)
Supernatants of myeloma monocytogenes (M20) were cultured in vitro to inhibit interleukin 1 (IL1) activity. A factor was isolated from the supernatant that inhibited the proliferation of mouse thymocytes induced by IL1 and also inhibited the proliferation of IL1-dependent lymphocytes and fibroblasts but did not inhibit IL2 induction Or other cell proliferation responses unrelated to IL1. From normal human peripheral blood mononuclear cells (PBMCs)