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Tinidazole(TDZ)是日本的一种抗原虫药物,广泛应用于治疗滴虫症.此药和甲硝哒唑同蛋咪唑簇.对厌氧菌有很好的抗菌效果.妇产科的感染主要是革兰氏阴性杆菌,近年来由于培养技术的进步和普及,厌氧菌分离率提高同时亦重视感染症的原因.本文山妇产科感染症病灶中培养需氧及厌氧菌,在了解细菌分布状态同时测定厌氧菌所致之感染症对TDZ的最低抑制浓度(MIC).口服TDZ临床观察的30例中子宫感染25例、阴道炎1例、外阴脓肿4例.治疗方法:TDZ1,000mg(500mg×2片)1次/日饭后口服.治疗日期3～28天.治疗前及治疗中作细菌培养测定厌氧菌的MIC.分离的厌氧菌:消化链球菌22株(44.9%),
Tinidazole (TDZ) is an antiprotozoal drug in Japan, which is widely used in the treatment of trichomoniasis. This drug and metronidazole with egg imidazole cluster have good antibacterial effect on anaerobic bacteria. Obstetrics and Gynecology infections mainly Is Gram-negative bacilli, in recent years due to the progress and popularization of culture technology, anaerobic bacteria separation rate also pay attention to the cause of infectious disease.In this paper, obstetrics and gynecology infectious diseases in aerobic and anaerobic bacteria in understanding The distribution of bacteria at the same time determine the minimum inhibitory concentration (MIC) of TDZ caused by anaerobic infections.Methods: 30 cases of oral TDZ clinical observation of 25 cases of uterine infection, 1 case of vaginitis, 4 cases of vulvar abscess treatment: TDZ1 , 000mg (500mg × 2 tablets) once / daily after meals orally. Treatment date 3 ~ 28 days before treatment and treatment of bacterial culture for the determination of MIC of anaerobic bacteria. Anaerobic bacteria isolated: Streptococcus 22 strains ( 44.9%),