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作者从胃癌组织中分离出粘膜单核样细胞(mo-nonuclear cells),检测抗体依赖性细胞介导的细胞毒性中 K 细胞的数量,用微量细胞毒性试验测定靶细胞的减少程度,并与来自胃癌及非癌病者身体其他部位的单核样细胞进行比较。研究胃癌部和正常胃粘膜单核祥细胞在局部细胞免疫反应中的作用。胃手术标本取自18例胃癌和3例胃溃疡;肠组织取自3例结肠癌;对照的正常胃粘膜取自离癌或溃疡病灶至少10cm 以外处,并经组织学证实正常;末梢血单核样细胞取自8名正常人、19例胃癌、3例胃溃疡和
The authors isolated mucosal mononuclear cells from gastric cancer tissue, detected the number of K cells in antibody-dependent cell-mediated cytotoxicity, determined the extent of target cell depletion using a microcytotoxicity assay, Gastric and non-cancer patients with other parts of the body of mononuclear cells were compared. To study the role of gastric cancer and normal gastric mucosa mononuclear cells in local cellular immune response. Stomach specimens were obtained from 18 gastric cancer and 3 gastric ulcer; intestinal tissue was taken from 3 colon cancer; normal gastric mucosa of the control was taken at least 10 cm away from the cancer or ulcer lesion and histologically confirmed; Nuclear-like cells were taken from 8 normal subjects, 19 gastric carcinomas and 3 gastric ulcers