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目的研究氯沙坦联合前列地尔注射液治疗慢性肾小球肾炎的效果。方法在我院2012年5月~2015年5月间收治的慢性肾小球肾炎患者中随机选出102例作为观察对象,将其按照治疗方法分成观察组和对照组,其中对照组患者采用氯沙坦治疗,观察组患者则加用前列地尔注射液治疗,就两组患者的相关疗效指标展开对比。结果观察组患者的总有效率92.31%高于对照组的82%,且观察组患者的24h尿蛋白定量、血肌酐、尿素氮、尿红细胞均明显低于对照组,P<0.05。结论氯沙坦与前列地尔注射液联合应用治疗慢性肾小球肾炎效果确切,有助于促进患者临床症状的缓解,提高生活质量,值得推广应用。
Objective To study the effect of losartan and alprostadil injection on chronic glomerulonephritis. Methods A total of 102 patients with chronic glomerulonephritis who were admitted to our hospital from May 2012 to May 2015 were selected randomly as the observation group and were divided into observation group and control group according to the treatment method. The patients in the control group were treated with chlorine Satan treatment, observation group patients were treated with alprostadil injection, the two groups of patients to compare the efficacy of indicators. Results The total effective rate of the observation group was 92.31% higher than that of the control group, and the urinary protein excretion, serum creatinine, urea nitrogen and urinary red blood cells in the observation group were significantly lower than those in the control group (P <0.05). Conclusion Losartan and alprostadil injection in combination with the treatment of chronic glomerulonephritis exact effect will help to promote the relief of clinical symptoms and improve quality of life, it is worth promoting the application.