目的 :评价沐舒痰片的祛痰疗效及安全性。方法 :在 2 46例有咳嗽、咳痰症状的呼吸系统疾病志愿受试患者中进行了一项前瞻性多中心的临床研究。结果 :受试患者的临控率为 66 3 % ,有效率为 92 7% ;对咳嗽、痰量、痰的性状、咳痰难度及肺部罗音等单项指标的有效率分别为 82 9%、 89 9%、 93 2 %、 80 0 %和 80 0 %。仅 1例患者用药后ALT轻度升高 ,2 8%的患者出现轻度不良反应。结论 :沐舒痰是安全有效的祛痰药。 Objective: To evaluate Mu Shu Sputum expectorant curative effect and safety. METHODS: A prospective, multicenter clinical study was conducted in 246 volunteers with respiratory conditions that had cough and phlegm symptoms. Results: The clinical trial rate was 66.3% and the effective rate was 92.7%. The effective rates of cough, sputum volume, phlegm traits, sputum difficulty and pulmonary rales were 82.9% , 89 9%, 93 2%, 80 0% and 80 0%. Only one patient had mildly elevated ALT after treatment and 28% had mild adverse reactions. Conclusion: Mu Shu Tan is a safe and effective expectorants.