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炎症介质的产生、释放在炎症反应和免疫调节等生物效应过程中发挥着重要作用,呼吸道炎症介质常常成为促发哮喘发作和加剧病情的主要因素,其中白细胞介素(IL-6)和肿瘤坏死因子(Tumor Necrosis Factors-α,TNF-α)是前炎症反应因子(PIC),它们在炎症反应中起重要作用。为此,我们检测了老年哮喘患者重症期、稳定期上述两种前炎症反应因子的变化,其意义探讨如下。
The production and release of inflammatory mediators play an important role in the biological effects such as inflammatory response and immune regulation. Inflammatory mediators of the respiratory tract often play a major role in the pathogenesis and aggravation of asthma. Interleukins (IL-6) and tumor necrosis Tumor necrosis factor alpha (TNF-alpha) is a pro-inflammatory response factor (PIC) that plays an important role in the inflammatory response. To this end, we examined the elderly patients with severe asthma, stable two kinds of changes in the former inflammatory response factors, the significance of the following discussion.