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由于卵巢颗粒细胞瘤患者血中可有较高水平的雌激素,抑制排卵,故合并妊娠机会很少,现报告1例。患者,25岁。因停经25周,腹胀近1月,双下肢浮肿1周,于1989年10月30日入院。查体T、P、R、Bp均正常,全身浅表淋巴结未触及,心肺正常。腹部膨隆,肝脾未触及,移动性浊音阴性,宫高24cm,可触及胎块,听到胎心音。肝功正常,血色素12g。B超:宫内胎儿正常。腹腔内有大量液性暗区,子宫左侧有12×13cm大小肿块,以实性为主,内有少量液性暗区。临床诊断:25周妊娠,左侧卵巢肿瘤。于1989年11月4日行剖腹术。手术所见:淡黄色腹水4000ml。子宫符合妊娠周数,色泽正常,左侧卵巢肿瘤约13×13×12cm大小,囊性,表面光滑,呈白色,同侧输卵管,对侧附件,大网膜,腹膜均正常。行左侧附件切除术。病理诊断:左侧卵巢颗粒细胞瘤Ⅱ级。于1990年1月27日自然分娩一女婴(体重3000g)。
As ovarian granulosa cell tumor blood in patients with higher levels of estrogen may inhibit ovulation, so few opportunities for merger pregnancy, is reported in 1 case. Patient, 25 years old. Due to menopause 25 weeks, bloating nearly 1 month, double lower extremity edema for 1 week, on October 30, 1989 admission. Physical examination T, P, R, Bp were normal, systemic superficial lymph nodes not touched, normal heart and lung. Abdominal bulge, liver and spleen not touched, voiced negative mobility, Palace height 24cm, palpable fetal block, heard fetal heart sound. Normal liver function, hemoglobin 12g. B-ultrasound: intrauterine fetal normal. Abdominal cavity with a large number of liquid dark area, the left uterine size of 12 × 13cm mass, mainly in solid, there are a small amount of liquid dark area. Clinical diagnosis: 25 weeks of pregnancy, left ovarian tumor. On November 4, 1989, laparotomy was performed. Surgical findings: pale yellow ascites 4000ml. The uterus consistent with the number of gestational weeks, normal color, the size of the left ovarian tumor about 13 × 13 × 12cm, cystic, smooth, white, ipsilateral tubal, contralateral annex, omentum, peritoneum are normal. Line left attachment excision. Pathological diagnosis: left ovarian granulosa cell tumor grade. On January 27, 1990 a natural delivery of a baby girl (weight 3000g).