论文部分内容阅读
目的:评价酚妥拉明联合丙种球蛋白治疗毛细支气管炎的疗效与安全性。方法:将毛细支气管炎患儿100例随机分为治疗组和对照组各50例,两组均采用抗感染、化痰、雾化表面激素治疗,治疗组另给予丙种球蛋白400mg/(kg·次),共用3 d,酚妥拉明0.5～1 mg/(kg·次),疗程为3～5 d。比较两组咳嗽、喘憋、气促、哮鸣音及湿啰音消失时间、血气分析及急诊留观天数。结果:治疗组在喘息、气促、肺部体征及血气分析好转等方面明显优于对照组,急诊留观日明显短于对照组(P<0.05)。结论:常规治疗毛细支气管炎基础上加酚妥拉明联合丙种球蛋白可快速缓解临床症状,缩短疗程。
Objective: To evaluate the efficacy and safety of phentolamine combined with gamma globulin in the treatment of bronchiolitis. Methods: One hundred children with bronchiolitis were randomly divided into treatment group and control group, 50 cases in each group. Anti-infective, phlegm and atomized surface hormones were used in both groups. Another 400 μg / kg Times) for 3 days and phentolamine 0.5 to 1 mg / (kg · times) for 3 to 5 days. Two groups were compared cough, wheezing, shortness of breath, wheeze and wet rales disappear time, blood gas analysis and emergency observation days. Results: The treatment group was superior to the control group in wheezing, shortness of breath, lung signs and blood gas analysis. The emergency observation day was significantly shorter than that of the control group (P <0.05). Conclusion: The conventional treatment of bronchiolitis combined with phentolamine combined with gamma globulin can quickly relieve clinical symptoms and shorten the course of treatment.