With the results of interpretation of seismic sounding profiles acquired in the past 30 years in the continent of China and its adjacent countries and ocean regions, such as Russia, Ka-zakhstan, Japan, India, Pakistan, Philippine ocean basin, Pacific and Indian Ocean, we compiled a 2D Moho distribution map for the continent and its adjacent areas of eastern Asia. From the fea-tures of depth distribution and undulation of Moho, it is suggested that the eastern Asian region can be divided into 18 gradient belts with different sizes, 18 crustal blocks, 20 sediment basins and depression zones. The depth of Moho varies smoothly in each block, while the boundary (separat-ing different blocks) delineates the abrupt variation of Moho depth. Then, some subjects,such as oregen and sediment basin, fault system and rift, plate boundary, ocean-continent coupling and tectonic framework, are discussed based on the distribution gradient belts and block partition fea-tures of Moho depth in the eastern Asia and its adjacent regions. With the results of interpretation of seismic sounding profiles acquired in the past 30 years in the continent of China and its neighboring countries and ocean regions, such as Russia, Ka-zakhstan, Japan, India, Pakistan, Philippine ocean basin, Pacific and Indian Ocean , we compiled a 2D Moho distribution map for the continent and its adjacent areas of eastern Asia. From the fea-tures of depth distribution and undulation of Moho, it is suggested that the eastern Asian region can be divided into 18 gradient belts with different sizes , 18 crustal blocks, 20 sediment basins and depression zones. The depth of Moho varies smoothly in each block, while the boundary (separat-ing different blocks) delineates the abrupt variation of Moho depth. Then, some subjects, such as oregen and sediment basin, fault system and rift, plate boundary, ocean-continent coupling and tectonic framework, are under based on the distribution gradient belts and block partition fea-tures of Moho depth in the eastern Asia and its adjacent regions.