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目的：探讨“氯－芬”合剂微泵法行小儿静脉全麻的效果及其对患儿呼吸、循环的影响。方法：５１例手术患儿（年龄４２ｄ～８岁，体重４～２２ｋｇ），用“氯－芬”合剂微泵滴注行非插管全凭静脉麻醉，术中监测ＭＡＰ，ＨＲ，ＲＲ，ＳｐＯ２，定时查动脉血气。结果：术中镇痛完善，患儿安静，分泌物少，停药后１０～３０ｍｉｎ苏醒。术中ＭＡＰ、ＨＲ、ＲＲ、ＳｐＯ２、ｐＨ和ＰａＣＯ２无明显变化（Ｐ＞０．０５）；ＰａＯ２和ＳａＯ２于术中１５ｍｉｎ显著高于术前（Ｐ＜０．０５）。结论：“氯－芬”合剂微泵法可控性强，给药均匀且用量少，镇静镇痛完善，对呼吸、循环影响轻微，术毕苏醒快，无明显并发症。
Objective: To investigate the effect of “Chlor-Fen” mixture micropump method on pediatric intravenous general anesthesia and its effects on respiration and circulation in children. METHODS: Totally 51 children undergoing surgery (age 42d-8, weight 4 ~ 22kg) were anesthetized by micro-pump infusion of “Chlorfenaphenamide” mixture. Intravenous monitoring of MAP, HR, RR and SpO2 Regular check arterial blood gas. Results: Intraoperative analgesia improved, children with quiet, less secretions, wake up after 10 ~ 30min. There were no significant changes in MAP, HR, RR, SpO2, pH and PaCO2 during operation (P> 0.05). PaO2 and SaO2 were significantly higher at 15 min in operation than those before operation (P <0.05). Conclusion: “Chlor-Fen” mixture micro-pump controllable, uniform administration and less dosage, sedation and analgesia perfect, little effect on respiration and circulation, rapid recovery after surgery, no significant complications.