吡喹酮是一种新型的广谱抗扁蠕虫药物,它可能是一种外消旋化合物。我们将合成吡喹酮的中间体拆分后而得到的左旋与右旋吡喹酮,进行了家兔实验治疗,这在国内外尚未见报道。从本文实验结果可见,不论减虫率、肝移率与虫体长度看来,均以左旋喹吡喹酮的疗效较消旋吡喹酮为优,而右旋吡喹酮组与对照组比较则无显著的统计学差别,故右旋吡喹酮的杀 Praziquantel is a new broad-spectrum anthelminthic agent that may be a racemic compound. We synthesized the intermediate of praziquantel and obtained the left-handed and the right-handed praziquantel. The experiment was done in rabbits, which has not been reported at home and abroad. From the experimental results we can see, regardless of the worm reduction rate, hepatic metastasis rate and the length of the parasites seems to be more effective than levo-praziquantel, and praziquantel compared with the control group There is no significant statistical difference, so the right to kill praziquantel