【摘 要】
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目的观察唑来磷酸治疗癌性骨痛的近期疗效和毒副作用。方法40例合并骨转移的恶性肿瘤患者给予唑来磷酸4mg+生理100ml,静脉滴注15min,28d为1个疗程,2个以上疗程评价疗效。结果
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目的观察唑来磷酸治疗癌性骨痛的近期疗效和毒副作用。方法40例合并骨转移的恶性肿瘤患者给予唑来磷酸4mg+生理100ml,静脉滴注15min,28d为1个疗程,2个以上疗程评价疗效。结果40例均可评价疗效,总有效率82.5%,临床获益率95%%。未发生明显不良反应。结论唑来磷酸治疗癌性骨痛疗效好,不良反应少见。
Objective To observe the short-term efficacy and side effects of zoledronic acid in the treatment of cancerous bone pain. Methods Forty patients with malignant tumor with bone metastasis were treated with zoledronic acid 4 mg + physiology 100 ml intravenously for 15 minutes and 28 days for one course of treatment. More than two courses of treatment were evaluated. Results All the 40 patients could evaluate the curative effect, the total effective rate was 82.5% and the clinical benefit rate was 95 %%. No obvious adverse reactions occurred. Conclusion Zoledronic acid treatment of cancer pain is good, rare adverse reactions.
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