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为评价比时间常数（Ｓτ）和Ｆ－Ｖ曲线形状在检查吸烟者小气道功能中的意义，对１１６例被动和轻、重度主动吸烟者进行了常规肺通气功能、Ｓτ和Ｆ－Ｖ曲线形状的研究。常规肺通气功能和Ｆ－Ｖ曲线形状用常规法测定。Ｓτ用公式Ｓτ＝１／·Ｖ计算。结果表明：凸型Ｆ－Ｖ曲线分布随吸烟程度加重而上升，·Ｖ５０、·Ｖ２５则下降及Ｓτ５０、Ｓτ２５延长在凸型与重度吸烟组一致。Ｓτ５０、Ｓτ２５延长的范围在凸型与重度吸烟组都是预计值的１２０％～１３０％，表明小气道功能有轻度障碍。与以前所测ＣＯＰＤ患者比较，其Ｓτ７５、Ｓτ５０、Ｓτ２５延长均加剧，表明大小气道都遭累及。故凸型、Ｓτ５０和Ｓτ２５延长、·Ｖ５０和·Ｖ２５下降都是检查小气道功能的敏感指标。可推荐临床应用参考。
To evaluate the significance of the time-dependent (Sτ) and F-V curve shapes in examining small airway function in smokers, routine pulmonary ventilation was performed in 116 passive and mild-to-severe active smokers and the Sτ and F-V curve shapes Research. Conventional pulmonary ventilation and F-V curve shapes were routinely determined. Sτ is calculated using the formula Sτ = 1 / · V. The results showed that the distribution of convex F-V curve increased with the increase of smoking degree, while the decrease of V50, V25 and the extension of Sτ50 and Sτ25 were consistent with that of the convex and severe smoking groups. The extended range of Sτ50 and Sτ25 was between 120% and 130% of the expected values in both the convex and severe smoking groups, indicating mild dysfunction in small airway function. Compared with the previously measured patients with COPD, Sτ75, Sτ50, Sτ25 extended exacerbations, indicating that the size of the airways have been involved. So convex, Sτ50 and Sτ25 extended, V50 and · V25 decline are sensitive indicators of small airway function check. Can recommend clinical application of reference.