目的　评价野中野照射加大剂量顺铂(HDPDD)水化技术在软组织肉瘤综合治疗中的地位及其疗效。方法　63 例软组织肉瘤术后患者随机分为研究组32 例( 野中野照射加HDPDD水化) ,对照组31 例( 常规照射、化疗)。研究组放射治疗:大野40 ～50 Gy,4 ～5 周,小野20 ～30 Gy,3～4 周,每天2 野照射,间隔6 小时;化疗:PDD80～100 mg/m2 ,每3 周1 次,共2 ～3 次。对照组放射治疗:40～50 Gy,4～5 周,后缩野加量20 ～30 Gy,2 ～3 周。结果　1,2 ,3 年生存率分别为93.8 % 和77.4% ,84 .4% 和64 .5% ,81.3 % 和58.1 %( P<0 .05)。研究组局部复发率和远地转移率降低,但与对照组比较差异无显著意义( P> 0.05) 。结论　野中野照射加HDPDD水化技术可在短时间内使肿瘤区接受较高剂量及获得放射治疗增敏,且明显提高了生存率,降低了局部复发率和远地转移率,作为术后综合治疗技术在软组织肉瘤治疗中具有重要价值 Objective To evaluate the status and efficacy of Yezhongye radiation-enhanced dose cisplatin (HDPDD) hydration technique in the comprehensive treatment of soft tissue sarcoma. Methods Sixty-three patients with soft tissue sarcoma were randomly divided into two groups: study group (32 cases with wild Nakano exposure plus HD-PDD hydration) and control group (31 cases with conventional irradiation and chemotherapy). Radiation therapy in the study group: Daye 40 to 50 Gy, 4 to 5 weeks, Ono 20 to 30 Gy, 3 to 4 weeks, 2 fields per day, interval 6 hours; chemotherapy: PDD 80 to 100 mg/m2, once every 3 weeks , 2 or 3 times in total. Radiotherapy for the control group: 40 to 50 Gy, 4 to 5 weeks, and 20 to 30 Gy for 2 hours to 3 weeks. Results The 1-, 2-, and 3-year survival rates were 93.8 % and 77.4%, 84.4% and 64.5%, 81.3% and 58.1%, respectively (P<0.05). The local recurrence rate and distant metastasis rate in the study group decreased, but there was no significant difference compared with the control group (P> 0.05). Conclusion Wild Nakano irradiation combined with HD-PDD hydration technology can increase the sensitivity of the tumor area receiving a higher dose and obtain radiotherapy in a short time, and significantly improve the survival rate, reduce the local recurrence rate and distant metastasis rate, as the surgery Post-combined therapy has important value in the treatment of soft tissue sarcoma