论文部分内容阅读
用免疫放射法检测３４例大肠癌患者血清ＭＧ－Ａｇｓ水平，并与３２例大肠良性疾病进行对照，结果发现：大肠癌组血清ＭＧ－Ａｇｓ水平高于对照组，差异显著（Ｐ＜０．０１）；血清ＭＧ－Ａｇｓ水平与病理分期、病理类型关系密切，Ａ期低于Ｂ、Ｃ、Ｄ期（Ｐ＜０．０１），高分化癌低于中低分化癌（Ｐ＜０．０１）；ＭＧ－Ａｇｓ水平与大肠癌病变环绕肠管的程度及肝转移与否均相关，环绕程度＞１／２者高于≤１／２者（Ｐ＜０．０１）；有肝转移者血清ＭＧ－Ａｇｓ水平高于无肝转移者（Ｐ＜０．０５）。此对大肠癌的诊断、治疗及估计预后有临床实用价值。
The serum MG-Ags levels in 34 patients with colorectal cancer were detected by immunoradiometric assay and compared with 32 benign colorectal diseases. The results showed that the levels of serum MG-Ags in the colorectal cancer group were significantly higher than those in the control group (P<0.01). Serum MG-Ags level was closely related to the pathological stage and pathological type, A stage was lower than B, C, D stage (P <0.01), well-differentiated carcinoma was lower than moderately-differentiated carcinoma (P <0.01). The level of MG-Ags was related to the extent of colorectal lesions surrounding the intestine and the liver metastasis. The degree of circumscribed>1/2 was higher than ≤1/2 (P<0.01); serum MG- Ags levels were higher than those without liver metastases (P<0.05). This has clinical and practical value for the diagnosis, treatment and estimated prognosis of colorectal cancer.