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目的 研究幽门螺杆菌（ Ｈｐ） 感染与小儿慢性胃炎、消化性溃疡病之间的关系，探讨 Ｈｐ的致病性。方法 我们对经胃镜检查证实的２４５ 例非溃疡性消化不良与６３ 例消化性溃疡患儿胃镜取材做 Ｈｐ 培养、快速尿素酶试验、病理学检查及血清 Ｈｐ Ｉｇ Ｇ 抗体测定。结果 在５６ 例十二指肠溃疡中 Ｈｐ 感染率为８３ ．９３ ％ ，７ 例胃溃疡为２８ ．５７ ％ ，２２４ 例慢性浅表性胃炎为４９ ．１１ ％ ，１１ 例慢性萎缩性胃炎为９０ ．０１ ％ ，其中３３ 例慢性活动性胃炎为９６ ．９７ ％ ，轻度胃炎为３２ ．７０ ％ ，中度胃炎为８３ ．７８ ％ ，而１０ 例正常胃粘膜者无１ 例发现 Ｈｐ 。结论 Ｈｐ 感染与小儿胃十二指肠疾病密切相关，尤其是活动性胃炎和十二指肠溃疡。
Objective To study the relationship between Helicobacter pylori (Hp) infection and chronic gastritis and peptic ulcer disease in children and to explore the pathogenicity of Hp. Methods 245 cases of non-ulcer dyspepsia confirmed by gastroscopy and 63 cases of peptic ulcer gastroscopy taken Hp culture, rapid urease test, pathological examination and serum Hp Ig G antibody. Results Hp infection rate was 56 in 56 cases of duodenal ulcer. 93%, 7 cases of gastric ulcer 28. 57%, 224 cases of chronic superficial gastritis 49. 11%, 11 cases of chronic atrophic gastritis 90. 01%, of which 33 cases of chronic active gastritis 96. 97%, mild gastritis is 32. 70%, 83 moderate gastritis. 78%, while none of the 10 normal gastric mucosa found Hp. Conclusion Hp infection is closely related to gastroduodenal diseases in children, especially active gastritis and duodenal ulcer.