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在 2 7只新西兰白兔胸大肌瓣转移的动物模型上 ,进行原神经支配、失神经后舌下神经植入再支配的比较研究 ,术后 4周、8周、12周和 16周行大体观察、光镜观察、激发肌电、神经免疫组化、肌瓣肌纤维多种酶组织化学染色的肌纤维组化分型检查。结果表明 ,失神经胸大肌瓣可重获舌下神经再支配 ,并在舌下神经支配下行使收缩功能 ,肌纤维的组化型别发生改变 ,从以酵解型纤维为主转化为以氧化型纤维为主 ,呈镶嵌分布模式 ,而类似于舌下神经原支配的肌肉。神经肌肉蒂植入在发生神经再支配的时间及范围方面优于神经直接植入。
In the animal model of 27 New Zealand white rabbits with pectoralis major flap transfer, the study of the original innervation and sublingual nerve implants after retina were compared. Four weeks, eight weeks, 12 weeks and 16 weeks after the operation Gross observation, light microscopy, excitation EMG, neuroimmunohistochemistry, myofibrillar multiple muscle tissue enzyme histochemical staining of muscle fiber type typing examination. The results showed that the denervated pectoralis major muscle flap could regain the sublingual hypoglossal reimplantation and exercise contractile function under the sublingual nerve. The histochemical types of the muscle fibers changed from predominantly glycolysis to oxidative Type fibers, was inlaid distribution patterns, and similar to the sublingual neurons dominate the muscles. Neuromuscular pedicle implantation is superior to direct nerve implantation in terms of the timing and extent of neurological disability.