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给出生１０ｄ内的雄性Ｗｉｓｔａｒ大鼠皮下注射谷氨酸单钠（ＭＳＧ），观察其新生期（１１日龄）、青春期（５２日龄）、成年期（１００日龄）的垂体生长激素（ＧＨ）细胞。结果：各期ＧＨ细胞的大小实验组均小于对照组，且随着年龄的增长差异越加明显，新生期有显著性差异（Ｐ＜０．００５），青春期与成年期均有高度显著性差异（Ｐ＜０．００１）。各期ＧＨ细胞中的ＧＨ含量实验组均高于对照组（Ｐ＜０．００１）。提示：注射谷氨酸单钠的雄性Ｗｉｓｔａｒ大鼠的垂体ＧＨ细胞的发育、成熟及其产生和分泌ＧＨ的功能均受到抑制。
Male Wistar rats were injected subcutaneously with glutamate monosodium glutamate (MSG) within 10 days of birth to observe the changes of pituitary growth hormone (GH) in the newborn (11 days), adolescence (52 days), adulthood (100 days) )cell. Results: The size of GH cells in each experimental group was smaller than that of the control group, and the difference was more obvious with age, the difference was significant at the neonatal period (P <0.005), and there was a highly significant difference between adolescent and adulthood (P <0.001). The levels of GH in GH cells in all experimental groups were higher than those in control group (P <0.001). It is suggested that the development, maturation, production of GH and secretion of GH in male Wistar rats injected with monosodium glutamate are inhibited.