论文部分内容阅读
目的:探讨胰腺混合性腺泡-神经内分泌癌(MANEC)的临床病理特征、鉴别诊断和治疗方法。方法:回顾性分析收治的1例胰腺MANEC患者的临床资料,结合国内外文献,总结该病的临床特点、病理特征、鉴别诊断和治疗方法。结果:该患者术前影像学检查提示十二指肠降部肿瘤,行手术治疗,术后病理提示胰腺MANEC。术后患者顺利出院,20个月后复查CT提示肿瘤无复发转移。结论:胰腺MANEC是非常罕见的肿瘤,常无典型的症状,最终需要病理确诊。预后至今不清楚,但是早期的手术治疗能显著提高总的生存期。
Objective: To investigate the clinicopathological characteristics, differential diagnosis and treatment of pancreatic mixed acinar-neuroendocrine carcinoma (MANEC). Methods: A retrospective analysis of 1 patient with pancreatic MANEC clinical data, combined with domestic and foreign literature, summarize the clinical features, pathological features, differential diagnosis and treatment. Results: The preoperative imaging examination showed that the descending duodenum tumor was surgically treated and postoperative pathology showed pancreatic MANEC. Postoperative patients were successfully discharged, 20 months after the review of CT prompt tumor recurrence and metastasis. Conclusions: Pancreatic MANEC is a very rare tumor with no typical symptoms and eventually requires pathological diagnosis. The prognosis remains unclear, but early surgical treatment can significantly improve the overall survival.