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目的 :探讨高原缺氧环境对高原地区老年人红细胞膜蛋白结构的影响 ;方法 :运用薄层色谱扫描等方法对长期居住在高原地区的 46例老人进行了红细胞膜磷脂蛋白和血液流变学等测定 ;结果 :高原组红细胞膜神经磷脂和磷脂酰胆碱等指标较平原组有显著升高 (P <0 .0 5或P <0 .0 1 ) ,血液粘度也有一定升高 ,以低切为明显 ;结论 :红细胞膜蛋白结构改变与高原缺氧有一定的关系。
Objective: To investigate the effect of plateau anoxic environment on the membrane structure of erythrocyte membrane in the elderly in plateau area.Methods: Thirty-six elderly people living in plateau area for long time were subjected to erythrocyte membrane phospholipid and hemorheology Results: The index of erythrocyte membrane phospholipid and phosphatidylcholine in the plateau group was significantly higher than that in the plain group (P <0.05 or P <0.01), and the blood viscosity was also increased to a certain extent As obvious; Conclusion: The structure of erythrocyte membrane protein has a certain relationship with plateau hypoxia.