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目的:探讨换血疗法治疗不同胎龄新生儿高胆红素血症的疗效及副作用。方法:将1991～2004年进行换血的56例新生儿按照胎龄分组,分析其疗效和副作用有无差异。结果:两组患儿换血后胆红素水平均显著降低(P<0.001)。早产儿换血后更易发生内环境紊乱,但差异无统计学意义(P>0.05)。结论:换血疗法治疗不同胎龄新生儿高胆红素血症疗效确切,尽管其所致的副作用如血生化异常、酸中毒、血小板减少症等通常可自我调节,但对早产儿而言仍不容忽视。
Objective: To investigate the curative effect and side effects of transfusing therapy on neonatal hyperbilirubinemia with different gestational age. Methods: 56 newborns who changed blood from 1991 to 2004 were divided into groups according to gestational age, and their differences in curative effect and side effects were analyzed. Results: The levels of bilirubin were significantly decreased in both groups (P <0.001). Premature babies exchange more prone to environmental disorders, but the difference was not statistically significant (P> 0.05). CONCLUSION: Transfusion therapy is effective in treating neonatal hyperbilirubinemia at different gestational ages. Although the side effects such as abnormal blood biochemistry, acidosis, thrombocytopenia and so on are usually self-regulating, they are still not suitable for preterm infants Neglect.