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克矽平(P204)化学名称为聚二——乙烯吡啶氮氧化物,我国于1964年合成并进行了大量药理试验等研究工作,肯定了对实验性矽肺的治疗效果。1967年开始用于临床其给药途径是雾化吸入,国内报导很多,并取得了丰富的临床经验。但是,雾化吸入远不能达到治疗作用所需的较大剂量,为此,我院在局党委和院党委的直接领导下与天津职业病防治院和天津医药工业研究所协作,由四川医学院卫生系具体参加指导,于1975年5月份开始使用低分子克矽平静脉滴注治疗矽肺的临床试用观察,目前仍在继续进行中,现将二年观察结果报告如下:
Ke Si-ping (P204) chemical name poly two - vinyl pyridine nitrogen oxides, China in 1964 synthesized and conducted a large number of pharmacological tests and other research work, affirmed the experimental treatment of silicosis. 1967 started its clinical route of administration is aerosol inhalation, many domestic reports, and has achieved a wealth of clinical experience. However, the inhalation is far unable to achieve the therapeutic effect of the larger dose required, therefore, our hospital in the bureau under the direct leadership of Party committees and hospital party committee and Tianjin Occupational Disease Prevention Institute and Tianjin Institute of Pharmaceutical Industry collaboration, by the Sichuan Medical College Health Department of specific guidance, in May 1975 began using low molecular weight polysilicon Ping intravenous treatment of clinical trial of silicosis observation, is still continuing, now the two-year observation report as follows: