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目的分析2009-2010年深圳市宝安区手足口病(hand-foot-mouth disease,HFMD)重症及死亡病例流行病学特征和主要危险因素。方法对2009-2010年报告的宝安区手足口病重症和死亡病例资料进行描述性分析,对51例重症患者进行流行病学调查。结果 2009-2010年宝安区共报告手足口病3 967例,发病率为58.7/10万,重症51例,死亡2例,重症病死率为3.9%。全区10个街道均有重症病例报告。各街道之间重症病例发生率的差异无统计学意义。时间分布上看4～9月份为手足口病发病高峰期。重症病例年龄分布在幼儿的各个年龄段。对50份样本进行检测,肠道病毒71型阳性率为82.0%。结论手足口病严重威胁宝安区幼儿的身体健康,重症病例病情进展快,病死率高。对手足口病患儿应提高警惕,及早救治。
Objective To analyze the epidemiological characteristics and major risk factors of severe and fatal cases of hand-foot-mouth disease (HFMD) in Bao’an District of Shenzhen City from 2009 to 2010. Methods Descriptive analysis of the data of severe and fatal cases of hand, foot and mouth disease in Baoan District from 2009 to 2010 was carried out. The epidemiological investigation of 51 severe cases was conducted. Results A total of 3 967 HFMD cases were reported in Baoan District from 2009 to 2010, with a prevalence of 58.7 / 100 000, 51 severe cases and 2 deaths. The critical mortality rate was 3.9%. District 10 streets have severe cases report. There was no significant difference in the incidence of severe cases among the streets. Time distribution from April to September the peak incidence of hand-foot-mouth disease. Severe cases of age distribution in young children of all ages. 50 samples were tested, the positive rate of enterovirus 71 was 82.0%. Conclusion Hand, foot and mouth disease seriously threatens the health of infants in Baoan District. The progress of severe cases is rapid and the case fatality rate is high. Children with foot-mouth disease should be vigilant, early treatment.