由于前列腺素具有广泛的药理作用,日益受到重视。本文是用D-半乳糖胺制作大白鼠急性肝损伤模型,从生化、病理及超微结构三方面对前列腺素E_1的肝细胞保护和治疗作用进行实验研究,为临床治疗肝炎提供实验依据。材料与方法一、实验对象:大白鼠共74只,SD纯种, As prostaglandins have a wide range of pharmacological effects, increasing attention has been paid to them. This article is to use D-galactosamine to make rats acute liver injury model, from biochemical, pathological and ultrastructural three aspects of prostaglandin E_1 hepatocyte protection and therapeutic effects of experimental studies, for clinical treatment of hepatitis to provide experimental basis. Materials and Methods 1. Experimental subjects: 74 rats, SD pure species,