肥大细胞是重要的效应和调节性免疫细胞,广泛分布于皮肤、淋巴组织、子宫、膀胱以及呼吸道和消化道黏膜和黏膜下毛细血管、淋巴管周围的结缔组织中。肥大细胞被激活,可以通过合成和释放相应介质导致支气管痉挛,血管的通透性增加以及其他的炎症预激反应。肥大细胞同时还释放一些 Mast cells are important effector and regulatory immune cells widely distributed in the skin, lymphoid tissues, uterus, bladder and respiratory and gastrointestinal mucosa and submucosal capillaries, connective tissue around lymphatic vessels. Mast cells are activated and can cause bronchospasm, increased vascular permeability, and other pro-inflammatory inflammatory responses through the synthesis and release of the corresponding mediators. Mast cells also release some at the same time