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目的探讨2型糖尿病对肺结核的临床表现和治疗效果的影响。方法我院2007年1-12月收治的2型糖尿病合并肺结核患者75例作为观察组(初治),另随机选出同期单纯肺结核患者80例作为对照组(初治),回顾性对比分析两组临床症状、痰菌涂阳率、胸部X线表现及抗结核疗效。结果观察组发热和咯血发生率以及痰菌涂阳率明显高于对照组(P<0.05);观察组胸部X线下肺野病变发生率明显高于对照组(P<0.05),病变类型以实变为主,空洞发生率也明显高于对照组(P<0.05)。12个月抗结核治疗后,观察组治疗总有效率和痰菌阴转率明显低于对照组(P<0.05)。结论2型糖尿病合并肺结核患者临床症状及胸部X线偏离典型单纯肺结核的表现,2型糖尿病对抗结核疗效有不利的影响。
Objective To investigate the effect of type 2 diabetes on clinical manifestations and treatment of pulmonary tuberculosis. Methods 75 cases of type 2 diabetes mellitus patients with tuberculosis admitted to our hospital from January 2007 to December 2007 were selected as the observation group (initial treatment). Another 80 cases of tuberculosis were randomly selected as the control group (initial treatment). The retrospective comparative analysis of two Group clinical symptoms, sputum smear rate, chest X-ray findings and anti-TB efficacy. Results The incidence of fever and hemoptysis and smear positive rate of sputum in the observation group were significantly higher than those in the control group (P <0.05). The incidence of lung field lesions in the chest X-ray group was significantly higher than that in the control group (P <0.05) Real change into the main, hollow incidence was significantly higher than the control group (P <0.05). After 12 months of anti-TB treatment, the total effective rate of observation group and sputum negative conversion rate was significantly lower than that of the control group (P <0.05). Conclusions The clinical symptoms of type 2 diabetic patients with pulmonary tuberculosis and the manifestations of chest X-ray deviations from typical simple pulmonary tuberculosis, type 2 diabetes have an adverse effect on the efficacy of anti-tuberculosis.