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化疗所致恶心、呕吐的发生占所有化疗病人的60％。“‘近年来的研究结果表明，”‘化疗药物所致的呕吐，主要是与化疗药物损伤胃肠道粘膜以及肠粘膜的嗜铬细胞释放5一羟色胺（5－hydroxytryptamine，5－HT）有关。现将5－HT与呕吐的关系综述如下，旨在为临床护理提供帮助。15－
Nausea and vomiting caused by chemotherapy account for 60% of all chemotherapy patients. “‘Research findings in recent years have shown that’ ‘the vomiting caused by chemotherapeutic drugs is mainly related to the damage of the gastrointestinal mucosa of chemotherapeutic drugs and the release of 5-hydroxytryptamine (5-HT) from the chromaffin cells of the intestinal mucosa. The relationship between 5-HT and vomiting is now summarized as follows to help clinical care. 15-