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目的:研究讨论采用米非司酮与甲氨蝶呤联合治疗输卵管妊娠的临床效果。方法:将我院2013年-2016年收治的300例输卵管妊娠患者分成甲组(n=150)和乙组(n=150),甲组患者使用米非司酮和甲氨蝶呤联合治疗,而乙组患者单纯以米非司酮治疗,比较两组不同药物治疗的效果。结果:甲组患者治疗的有效率为92.00%,乙组治疗有效率为84.66%,组间治疗效果比较差异显著(P<0.05);甲乙组患者治疗后的盆腔包块直径和血β-HCG值都小于治疗前,且甲组患者住院时间比乙组患者短,差异有统计学意义(P<0.05);甲组出现不良反应的几率与乙组没有明显差异(P>0.05)。结论:以米非司酮联合甲氨蝶呤治疗输卵管妊娠有显著的临床效果,治疗的不良反应小。
Objective: To study and discuss the clinical effect of combined treatment of tubal pregnancy with mifepristone and methotrexate. Methods: A total of 300 tubal pregnancy patients admitted to our hospital from 2013 to 2016 were divided into two groups (n = 150) and group B (n = 150). Patients in group A were treated with mifepristone and methotrexate, However, patients in group B were treated with mifepristone alone, and the effects of different drug treatments in both groups were compared. Results: The effective rate of treatment in group A was 92.00%, the effective rate in group B was 84.66%, and there was significant difference between the two groups (P <0.05). After treatment, the pelvic mass diameter and blood β-HCG (P <0.05). The incidence of adverse reactions in group A was not significantly different from that in group B (P> 0.05). Conclusion: The combination of mifepristone and methotrexate tubal pregnancy has a significant clinical effect, the treatment of adverse reactions.