伤寒的诊断有赖血培养及肥达反应,但其阳性率受到发病初期应用抗生素的影响,部份患者肥达反应始终阴性,宜探求一种早期确诊的方法。本文采用乳胶凝集试验(LAT)及葡萄球菌协同试验(SCT)检测大鼠感染伤寒菌后Vi抗原出现情况、持续时间,与血及尿中伤寒菌存在的关系,并在对照治疗中进行观察。 The diagnosis of typhoid fever depends on the blood culture and Widal response, but the positive rate by the onset of the application of antibiotics, some patients always have a negative response to Widal, should seek an early diagnosis. In this paper, latex agglutination test (LAT) and staphylococcal synergy test (SCT) were used to detect the occurrence and duration of Vi antigens in rats infected with typhoid fever, and the relationship between blood and urinary thallus and observed in the control treatment.