论文部分内容阅读
目的:研究芪蟾口服结肠靶向片(浸膏)及组成药味提取物体外抗氧化作用。方法:采用体外试验,对芪蟾口服结肠靶向片(浸膏)及组成药味提取物抑制红细胞溶血、抑制大鼠肝匀浆自发性脂质过氧化、清除DPPH自由基能力、还原能力、清除·OH能力等多个方面进行了系统研究。结果:芪蟾口服结肠靶向片(浸膏)及组成药味提取物对红细胞溶血均具有很好的保护作用,能有效地抑制肝匀浆自发性过氧化;并能有效地清除DPPH自由基以及·OH;对铁离子均具有良好的还原能力。结论:芪蟾口服结肠靶向片(浸膏)及组成药味提取物均具有良好的体外抗氧化能力。
OBJECTIVE: To study the anti-oxidative effect of oral administration of Radix Astragalus to the colon-targeted tablets (extract) and its constituents. Methods: In vitro experiment, oral administration of Radix Astragalus to the colon targeting tablets (extract) and composition of the drug extract inhibit hemolysis of red blood cells, inhibition of spontaneous lipid peroxidation in rat liver homogenate, scavenging DPPH free radical capacity, reducing capacity, clearance · OH ability and other aspects of a systematic study. Results: The oral administration of Radix Astragali and Radix Salviae Miltiorrhizae could effectively inhibit the spontaneous peroxidation of liver homogenate and effectively scavenge DPPH free radical as well as · OH; iron ions have good reducing power. Conclusion: Astragalus salivary oral colon targeting tablets (extract) and the composition of herbal extracts have good antioxidant capacity in vitro.