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应用米托蒽醌与阿克拉霉素联合化疗方案，治疗成人难治性急性白血病10例。结果完全缓解率50％，部分缓解率40％，总有效率90％。主要毒副作用为严重的骨髓抑制及一过性肝功能损害等。结果表明：本联合化疗方案对于成人难治性急性白血病具有疗效高、副作用小的优点。
A combination chemotherapy with mitoxantrone and aclacinomycin was used to treat 10 cases of refractory acute leukemia in adults. Results The complete remission rate was 50%, the partial remission rate was 40%, and the total effective rate was 90%. The major toxic side effects are severe bone marrow suppression and transient liver damage. The results showed that this combined chemotherapy regimen has the advantages of high efficacy and small side effects for adult refractory acute leukemia.