论文部分内容阅读
目的:观察中药合小剂量激素治疗慢性马兜铃酸肾病(CAAN)临床疗效。方法:27例慢性马兜铃酸肾病患者,中药治疗:肾衰康胶囊,虫草黄芪补益胶囊,口服;肾衰1号煎剂,每日1剂,口服;阿魏酸钠200mg静点,每日1次。激素:地塞米松3~4mg隔日入壶静点,7次,2~3mg隔日入壶静点,7次,出院后,泼尼松10mg天/,口服,1年,5mg天/,口服,半年。结果:治疗后患者中医各项症状改善明显,治疗1、6个月BUN、Scr、Ccr、Hb、ANG、β2微球蛋白,治疗前后比较差异具有统计学意义(P<0.05,P<0.01)。其中显效11例,有效13例,无效3例,总有效率88.89%。结论:中药合小剂量糖皮质激素治疗患者肾功能得以恢复。
Objective: To observe the curative effect of Chinese medicine combined with small dose hormone on chronic aristolochic acid nephropathy (CAAN). Methods: 27 cases of patients with chronic aristolochic acid nephropathy, traditional Chinese medicine treatment: Shenshenkang Capsule, Cordyceps Huangqi Bu Yi Capsule, oral; Decoction of kidney failure 1 day, oral; 200mg sodium ferulate static point, each 1 day. Hormone: dexamethasone 3 ~ 4mg into the kettle the next day, 7 times, 2 ~ 3mg into the kettle the next day, 7 times, after discharge from the hospital, prednisone 10mg day /, orally, 1 year, 5mg days / Six months. Results: After treatment, the symptoms of Chinese medicine were significantly improved. The levels of BUN, Scr, Ccr, Hb, ANG, β2 microglobulin at 1 and 6 months after treatment were significantly different between before and after treatment (P0.05, P0.01) . Among them, 11 cases were markedly effective, 13 cases were effective, 3 cases were ineffective and the total effective rate was 88.89%. Conclusion: Chinese medicine combined with low-dose glucocorticoid treatment of renal function was restored.