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小檗碱(Ber)0.1～300μmol/L对豚鼠离体右心房肌和孔头状肌呈现剂量依赖性正性变力作用,并末见到小剂量加强心肌收缩力,较大剂量抑制心肌收缩力的“双相作用”,对右心房则显示剂量依
Berberine (Ber) 0.1-300μmol/L showed a dose-dependent positive inotropic effect on isolated right atrium and pterygoid muscle of guinea pigs. At the end of the experiment, small doses increased myocardial contractility, and higher doses inhibited myocardial contraction. The “biphasic effect” of force shows doses to the right atrium.