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本文报道制备的抗人淋巴白血病细胞表面分化抗原的单抗 HI30 CIgG1)与抗癌药柔红霉素、甲氨喋呤、丝裂霉素以及蓖麻毒素及其A链连接成免疫偶合物及免疫毒素。用间接免疫荧光法在体外测定这些免疫偶合物和免疫毒素与靶细胞—人白血病细胞CME细胞株特异
The anti-human lymphoblastic cell surface differentiation antigen monoclonal antibody HI30 CIgG1) and the anti-cancer drugs daunorubicin, methotrexate, mitomycin, ricin and its A chain were immunoconjugate. Immunotoxins. Measurement of these immunoconjugates and immunotoxins with target cell-human leukemia cell CME cell line in vitro using indirect immunofluorescence