嗜酸性粒细胞(Eo)是日本血吸虫病虫卵肉芽肿的主要成分。近来认为细胞介导的免疫反应参与该虫引起的免疫病理。作者通过实验证实感染小鼠脾细胞可产生ECF-L。雄性C57BL/6小鼠,鼠龄5-6周,重约17克,每只腹腔内注入日本血吸虫(日本株)尾蚴30个。六周后取出脾脏,在冷Hank’s平衡盐溶液(HBSS)中用两张玻片 Eosinophils (Eo) is the main component of Schistosomiasis japonicum egg granuloma. Recently, it is considered that the cell-mediated immune response is involved in the immune pathology caused by this insect. The authors experimentally confirmed that infected mouse spleen cells produce ECF-L. Male C57BL / 6 mice, aged 5-6 weeks and weighing about 17 grams, were injected intraperitoneally with 30 cercariae of Schistosoma japonicum (Japanese strain). Spleens were removed six weeks later and two slides were taken in cold Hank’s balanced salt solution (HBSS)